What Is Satellite Dna
The name satellite refers to the early observation that centrifugation of genomic dna in a test tube separates a prominent layer of bulk dna from accompanying satellite layers of repetitive dna.
What is satellite dna. Satellite dna is a type of repetitive dna which is highly repeated. There can be several different types of satellite dna in a particular genome with. Satellite dna definition is a fraction of a eukaryotic organism s dna that differs in density from most of its dna as determined by centrifugation that consists of short repetitive nucleotide sequences that does not undergo transcription and that is often found in centromeric regions. The name satellite dna refers to the phenomenon that repetitions of a short dna sequence tend to produce a different frequency of the bases adenine cytosine guanine and thymine and.
Satellite dna is located on specific chromosomes and centromeres of the chromosomes. It carries a variable at rich repeat unit that often forms arrays up to 100 mb. Repetitive dna is located in the intergenic regions of the genome. What is satellite dna.
Satellite dna are tandemly repeated and located in the centromere and telomere regions of chromosomes. One class of this dna alpha satellite comprises up to 10 of the genome. Alpha satellite is enriched at all human centromere regions and is competent for de novo centromere assembly. The monomer length of satdna sequences ranges from 150 to 400 bp in the majority of plants and animals.
Minisatellites are small sequences of dna that do not encode proteins but appear throughout the genome hundreds of times with many repeated copies. The density of dna is a function of its base and sequence and satellite dna with its highly repetitive dna has a reduced or a characteristic density compared to the rest of the genome. Repetitive dna formerly referred to by the misnomer junk dna comprises a majority of the human genome. Satellite dna satdna is the highly repetitive dna consisting of short sequences repeated a large number of times.
Satdna sequences are located at heterochromatic regions which are found mostly in centromeric. Genome dispersed repeats and 3 satellite dna which contains short nucleotide sequences repeated as many as thousands of times. Because of the highly repetitive nature of alpha satellite it has been difficult to achieve genome. Such repeats are often found clustered in tandem near the centromeres i e the attachment points for the nuclear spindle fibres that move chromosomes during cell division.
They belong to the category of repetitive dna called tandem repeats. Satellite dna consists of very large arrays of tandemly repeating non coding dna satellite dna is the main component of functional centromeres and form the main structural constituent of heterochromatin. Satellite dna consists of highly repetitive sequences 10 6 repeats per genome.